BPC-157

Body Protection Compound 157

Evidence & Status

  • Preliminary / Experimental
  • Preliminary

At a Glance

A research peptide derived from a protective protein found in gastric juice, commonly studied for its potential roles in tissue healing and recovery. Most frequently explored in research involving tendons, ligaments, muscles, and the gastrointestinal tract.

Plain English

Researchers study BPC-157 because it appears to play a role in how the body initiates and sustains healing after injury. Scientists are particularly interested in its potential connections to tendon and ligament repair, gut lining health, and the control of inflammation. Much of the existing research has been conducted in animal models, and scientists continue to explore how these findings may relate to human biology. It is often discussed in recovery-focused research literature alongside other tissue-repair compounds.

Overview

A 15-amino-acid peptide sequence associated with gastric-juice research. Published evidence is predominantly preclinical; animal findings in tissue and gastrointestinal models have not established clinical efficacy or safety in people.

Research Summary

The available evidence base is primarily preclinical. Limited human exposure data exist: a small 2025 pilot study examined intravenous BPC-157 administration in two participants and reported no serious acute adverse events, but this study was too small to establish clinical efficacy, long-term safety, or a pharmacokinetic profile (Lee and Burgess 2025). No adequately powered, controlled human efficacy program was identified in this review, and animal findings should not be interpreted as established clinical benefit. A July 2026 Pharmacy Compounding Advisory Committee discussion was advisory only and does not constitute FDA approval or a final FDA determination.

Research Areas

  • Tendon healing
  • Gut health
  • Neuroprotection
  • Anti-inflammatory
  • Muscle repair

Safety & Risks

Serious Risks

  • Human safety, pharmacokinetics, and long-term outcomes have not been established

Reported Side Effects

  • Nausea (uncommon)
  • Injection site redness
  • Dizziness (rare)
  • Vivid dreams (anecdotal)
United States
Research only
United Kingdom
Research only
Australia
Research only
Canada
Research only

Citations & Sources